Our very own Ryan West, Product Manager for Development will be accompanied by Frédéric Bébien, Product Development & TCS Manager from the Lab & Life Science Business Unit at AHLSTROM, a global leader in sustainably-sourced, fiber-based specialty materials, to provide information on the numerous factors that need to be considered for designing a lateral flow assay (LFA).
Once limited to testing labs, lateral flow assay (LFA) technology has come of age in the post-pandemic world. For manufacturing, these rapid tests have multiple components that must be optimized. Learn more about the key components and reaction schemes.
A variety of conjugation chemistries are used to immobilize molecules such as antibody, peptide, or proteins to magnetic or polystyrene beads. Use our go-to guide for tips and basic protocols on how to covalently attach a molecule to microparticles.
In this recent Nature Review—Bioengineering, the authors describe the use of lateral flow assays, the key barriers to their development, and how the pandemic was affected by access. The article presents a nice review of the principles of LFA designs and suggests ways to create LFAs that are REASSURED (having Real-time connectivity, Ease of sample
preparation, Affordable, Sensitive, Specific, User-friendly, Robust and reliable, Equipment free or environmentally friendly, and Deliverable to the user). In addition, the review summarizes some of the next generation of LFAs, which employ LAMP, CRISPR, and RT-PCR for increased sensitivity.
Properties of the nitrocellulose membrane used in a lateral flow test can interfere with the chemistry of the analyte detection strategy especially if the analyte is a nucleic acid. This article compares different strategies
for binding a nucleic acid to nitrocellulose via anti-biotin antibodies, nitrocellulose- binding streptavidin, streptavidin, and polystreptavidin. They investigated the number of striping passes, rinse conditions, and test stripe and control stripe widths for finding high-density capture surfaces that increase the signal in nucleic acid hybridization applications.
Ethos Biosciences and Bangs Labs will be co-exhibiting at ADLM (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), to answer any questions you may have about these products and more!
Your can also visit our collaborator, AHLSTROM, at Booth #1443.
Come see us at Booth #3849 to get some free swag--we would love to meet you!
Visit Ethos Biosciences at the National Society for Histotechnology Convention in New Orleans, where we can answer any of your questions about histology and hematology dyes and stains, reagents, and/or buffers for retail, bulk, private label, and contract manufacturing.
September 20-24, 2024
Don't miss out on great science in a great location!
Join us in San Diego, CA between October 23-27, 2024 for the conference and visit us in Booth #2526.
Ethos offers a line of ELISAs focused on nephrology research to advance the molecular understanding of kidney diseases. Through our partnership with PrognostX Health™, we also are developing an ELISA that has a promising biomarker for kidney disease detection.
What we're reading this month:
Every year the Royal Society picks out a short list of books that engage the reader to think deeper and examine the world from a scientific point of view.
This book presents information about the sensory lives of animals. It simulates the readers curiosity and imagination by empathizing with the animal experience. By breaking the book into chapters for each of the senses and finding a protagonist for each (whether animal or scientist), this book will provide a new perspective on how animals perceive the world around them. It was awarded the Royal Society Trivedi Science Book Prize in 2023.
SARS-CoV-2 is the protagonist for the book and was written based on Zoom interviews during the pandemic. The author wanted this to be a comprehensive scientific work told through the lens of the researchers that were doing the experiments. He walks us through a chronological recount of the people and experiments that were done to understand how the virus evolved, how it killed, and how to control its spread.
Is science a meritocracy? Is this the one career where you are awarded on the work and not gender? This book describes the story of sixteen women scientists who started their careers in the 1960s and learned through experiences that women were still experiencing discrimination. The book describes how the group, with a focus on Nancy Hopkins, seeded changes in how women are perceived and treated in science.
If you like what you see, click below to sign up for your own copy! Every so often we'll send you a newsletter like this one and, best of all, we promise not to fill up your inbox. Or if you don't want any more emails, you can access this content by subscribing through LinkedIn.
