Learn all about Lateral Flow Assays with featured webinars, products, and articles.
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Newsletter Logo_TITRATIONS Ethos Biosciences

June 2024

Things you need to know...

quick-III-set

NEW LOWER PRICES!

Some of our most popular Astral Dyes & Stains are now more cost-effective for you! Price reductions are effective immediately and include:

  • Wright's Stain
  • Differential Quick III Set 
  • Gram Stain Safranin, 1 Gal.
  • And many more!

 

Check out our upcoming webinar

Ethos and Ahlstrom webinar image

Our very own Ryan West, Product Manager for Development will be accompanied by Frédéric Bébien, Product Development & TCS Manager from the Lab & Life Science Business Unit at AHLSTROM, a global leader in sustainably-sourced, fiber-based specialty materials, to provide information on the numerous factors that need to be considered for designing a lateral flow assay (LFA). 

 

With AHLSTROM's focus on membranes and Ethos' focus on LFA manufacturing, the webinar will provide the basic information needed to take your LFA from development to manufacturing. 

 

More information coming to your inbox on July 10!

LFA Kit with wick pads, backing card, cassette, membranes, sample pads

Lateral Flow Assay Starter Kit

Our latest product release has different nitrocellulose membranes and conjugate / sample pads to determine the optimal combination for your LFA.

 

AHLSTROM nitrocellulose

AHLSTROM conjugate pads

AHLSTROM sample pads

ETHOS BIOSCIENCES LFA manufacturing knowledge & CDMO

Order now
Complementary LFA Nanoparticle Products

from Bangs Labs, part of the Ott Scientific family of companies

Images Eu III

Europium Chelate Nanoparticles

 

• Carboxylated surface for covalent attachment

• Long Stokes shift for time resolved fluorescence

• Available individually or in a Sampler Pack of 4 different diameters

OD1 colloidal gold bottles

 

Colloidal Gold 

 

• 40 nm diameter

• OD1 and OD 5 available now

• 20 nm and 30 nm coming soon!

• Manufactured under ISO13485:2016 Quality System

Dyed Beads Chart _icons

 

Dyed Polystyrene

 

 • Available in a variety of diameters and colors

• Non-functionalized, carboxylated, or streptavidin-coated

• Standard volumes from 0.5 – 5.0 g of 5% solids

TechNote303

TECHNOTE 303, Lateral Flow Assays

Once limited to testing labs, lateral flow assay (LFA)  technology has come of age in the post-pandemic world. For manufacturing, these rapid tests have multiple components that must be optimized.  Learn more about the key components and reaction schemes.

Get your own copy here.

TECHNOTE 205, Covalent Coupling

A variety of conjugation chemistries are used to immobilize molecules such as antibody, peptide, or proteins to magnetic or polystyrene beads. Use our go-to guide for tips and basic protocols on how to covalently attach a molecule to microparticles.

Get your own copy here.

TechNote 205
The Science Snapshot Logo

We picked out a few interesting publications that discuss lateral flow assays:

Lateral flow test engineering and lessons learned from COVID-19

In this recent Nature Review—Bioengineering, the authors describe the use of lateral flow assays, the key barriers to their development, and how the pandemic was affected by access. The article presents a nice review of the principles of LFA designs and suggests ways to create LFAs that are REASSURED (having Real-time connectivity, Ease of sample 

lateral flow-2

Budd, J, Miller, BS, Weckman, NE, Cherkaoui, et al. (2023). Nature Reviews Bioengineering, 1(1), 13-31. https://doi.org/10.1038/s44222-022-00007-3

preparation, Affordable, Sensitive, Specific, User-friendly, Robust and reliable, Equipment free or environmentally friendly, and Deliverable to the user). In addition, the review summarizes some of the next generation of LFAs, which employ LAMP, CRISPR, and RT-PCR for increased sensitivity. 

Concept of biochemistry with dna molecule on blue background

Hallerbach, K, Khederlou, K, Wentland, L, Senten, L, Brentano, S, Keefe, B, & Fu, E. (2023). Micromachines (Basel), 14(10). https://doi.org/10.3390/mi14101936

Protein-Based Anchoring Methods for Nucleic Acid Detection in Lateral Flow Format Assays

Properties of the nitrocellulose membrane used in a lateral flow test can interfere with the chemistry of the analyte detection strategy especially if the analyte is a nucleic acid. This article compares different strategies  

for binding a nucleic acid to nitrocellulose via anti-biotin antibodies, nitrocellulose- binding streptavidin, streptavidin, and polystreptavidin. They investigated the number of striping passes, rinse conditions, and test stripe and control stripe widths for finding high-density capture surfaces that increase the signal in nucleic acid hybridization applications.

Out and About

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ADLM 2024 (Association for Diagnostics & Laboratory Medicine)

Ethos Biosciences and Bangs Labs will be co-exhibiting at ADLM (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), to answer any questions you may have about these products and more! 

For more information, check out our overview video and event webpage.

 

Your can also visit our collaborator, AHLSTROM, at Booth #1443. 

 

Come see us at Booth #3849 to get some free swag--we would love to meet you!

2024 National Society for Histotechnology Convention Logo

Visit Ethos Biosciences at the National Society for Histotechnology Convention in New Orleans, where we can answer any of your questions about histology and hematology dyes and stains, reagents, and/or buffers for retail, bulk, private label, and contract manufacturing.

September 20-24, 2024

Don't miss out on great science in a great location! 

Lanyard with Kidney Week 2024 logo

Join us in San Diego, CA between October 23-27, 2024 for the conference and visit us in Booth #2526.

American Society of Nephrology (ASN) Kidney Week 2024

Ethos offers a line of ELISAs focused on nephrology research to advance the molecular understanding of kidney diseases. Through our partnership with PrognostX Health™, we also are developing an ELISA that has a promising biomarker for kidney disease detection.

 

ethos reads and listens logo

What we're reading this month:

Every year the Royal Society picks out a short list of books that engage the reader to think deeper and examine the world from a scientific point of view. 

    AdobeStock_683710202

    This book presents information about the sensory lives of animals. It simulates the readers curiosity and imagination by empathizing with the animal experience. By breaking the book into chapters for each of the senses and finding a protagonist for each  (whether animal or scientist), this book will provide a new perspective on how animals perceive the world around them. It was awarded the Royal Society Trivedi Science Book Prize in 2023.

    AdobeStock_405153411

    SARS-CoV-2 is the protagonist for the book and was written based on Zoom interviews during the pandemic. The author wanted this to be a comprehensive scientific work told through the lens of the researchers that were doing the experiments. He walks us through a chronological recount of the people and experiments that were done to understand how the virus evolved, how it killed, and how to control its spread.

    AdobeStock_250425935

    Is science a meritocracy? Is this the one career where you are awarded on the work and not gender? This book describes the story of sixteen women scientists who started their careers in the 1960s and learned through experiences that women were still experiencing discrimination. The book describes how the group, with a focus on Nancy Hopkins, seeded changes in how women are perceived and treated in science.

    Find these books and more on our GoodReads® list

    And if you're thinking... I ain't got time for all that readin'...

    Check out all our favorite Spotify® podcasts

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